Physiological Alterations in Blood and Kidney Function in Malnourished Patients Implications for Health Management

Abstract

Background
Malnutrition is a serious public health issue in low-income countries, particularly in Yemen. The early detection and management of malnutrition are crucial for preventing complications and improving patient outcomes. Blood tests can be used as a diagnostic tool for malnutrition, but their effectiveness in Yemen has not been adequately investigated. This study aimed to assess the blood and kidney function of malnourished patients in Yemen and identify markers for early detection and diagnosis of malnutrition.

Methods
A total of 10 clinically suspected malnourished patients were included in the experimental group, and 10 healthy individuals without any health problems were included in the control group. Blood and urine samples were collected from both groups, and a wide range of blood tests were conducted, including complete blood count, renal function tests, electrolytes, liver function tests, and lipid profile. Data were analyzed using statistical tests.

Results
The results showed a significant difference between the two groups in terms of White Blood Cell Count (WBC), Red Blood Cell Count (RBC), Hemoglobin (HB), and Platelet Count (PIT) counts (P=0.005). The laboratory investigations also revealed significant abnormalities in the blood and kidney function of the malnourished patients compared to the healthy controls, indicating that malnutrition negatively impacts blood parameters and kidney function.

Conclusion
The study identified markers for early detection and diagnosis of malnutrition and demonstrated the usefulness of blood tests as a diagnostic tool for malnutrition in Yemen. Early detection and management of malnutrition can help prevent complications and improve patient outcomes, highlighting the importance of proper nutrition for maintaining normal physiology, particularly in areas affected by malnutrition such as Hajjah City in Yemen.